SuO022SERUM URIC ACID & DECLINE IN RENAL FUNCTION > THE ARAGON WORKERS’ HEALTH STUDY COHORT
نویسندگان
چکیده
منابع مشابه
Aragon workers’ health study – design and cohort description
BACKGROUND Spain, a Mediterranean country with relatively low rates of coronary heart disease, has a high prevalence of traditional cardiovascular risk factors and is experiencing a severe epidemic of overweight/obesity. We designed the Aragon Workers' Health Study (AWHS) to characterize the factors associated with metabolic abnormalities and subclinical atherosclerosis in a middle aged populat...
متن کاملUric Acid and Decline in Renal Function-Partners in Crime.
treated for hypertension in the UK [3] . A novel finding from this study was that an increase in serum uric acid over a 5-year period was associated with a greater decline in eGFR (OR 3.77, 95% CI 3.35–4.26 for each 1 mg/dL increase). Whilst, as the authors acknowledge, dissecting an independent effect of uric acid on decline in eGFR is challenging due to the effect of reducing kidney function ...
متن کاملUric Acid and Renal Function
Since the discovery of hyperuricemia as the cause of gout in the early 1800s, hypertension, cardiovascular disease and kidney disease have also been related to increased serum uric acid (UA) levels in subsequent years (Nakagawa et al., 2006); patients with gout had a much higher prevalence of hypertension (25-50%), mild-to-moderate kidney disease (20-60%) (Kutzing & Firestein, 2008) and cardiov...
متن کاملUric acid is associated with the rate of residual renal function decline in peritoneal dialysis patients.
BACKGROUND Uric acid (UA) is known to play a pathogenic role in chronic kidney disease (CKD). However, its effect in end-stage renal disease (ESRD) has not yet been elucidated. We explored the prevalence of hyperuricaemia and the relationship between UA and residual renal function (RRF) in peritoneal dialysis (PD) patients. METHODS The subjects of this study were 134 PD patients who started d...
متن کاملAssociations among Lead Dose Biomarkers, Uric Acid, and Renal Function in Korean Lead Workers
Recent research suggests that both uric acid and lead may be nephrotoxic at lower levels than previously recognized. We analyzed data from 803 current and former lead workers to determine whether lead biomarkers were associated with uric acid and whether previously reported associations between lead dose and renal outcomes were altered after adjustment for uric acid. Outcomes included uric acid...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2018
ISSN: 0931-0509,1460-2385
DOI: 10.1093/ndt/gfy104.suo022